Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.010 AlteredExpression BEFREE These results suggest that a single injection of duloxetine suppressed mechanical hyperalgesia and may influence the expression of Iba1 in the microglia of the ipsilateral dorsal horn in the MIA-induced hip OA. 31538672

2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.030 Biomarker BEFREE The data might suggest a difference in the etiology of hip OA from that of the knee OA, perhaps due to an unknown dissimilarity in vulnerability of these joints to the actions of IL17. 31042000

2019
Entrez Id: 112744
Gene Symbol: IL17F
IL17F
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.010 GeneticVariation BEFREE The haplotype G-T (IL17A-IL17F; rs2275913-rs763780) is associated with protection to the disease in hip OA (p < 0.01). 31042000

2019
Entrez Id: 7412
Gene Symbol: VCAM1
VCAM1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.010 Biomarker BEFREE The results of this study show that serum concentrations of VCAM-1 cannot distinguish patients with severe hip OA from age and sex-matched controls. 31037360

2019
Entrez Id: 55660
Gene Symbol: PRPF40A
PRPF40A
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.010 GeneticVariation BEFREE Ten individuals at high risk of developing hip osteoarthritis (SibKids) underwent contemporaneous T2 mapping and dGEMRIC in the hip (10 hips). 30971110

2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.010 Biomarker BEFREE Overall our findings provide direct evidence about the importance of β-catenin in hip OA pathogenesis. 30912140

2019
Entrez Id: 5339
Gene Symbol: PLEC
PLEC
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.110 AlteredExpression BEFREE GRINA and PLEC also demonstrated differential expression between OA hip and non-OA hip cartilage. 30730609

2019
Entrez Id: 2907
Gene Symbol: GRINA
GRINA
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.010 AlteredExpression BEFREE GRINA and PLEC also demonstrated differential expression between OA hip and non-OA hip cartilage. 30730609

2019
Entrez Id: 1301
Gene Symbol: COL11A1
COL11A1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.440 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.440 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 3589
Gene Symbol: IL11
IL11
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.410 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 3589
Gene Symbol: IL11
IL11
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.410 Biomarker CTD_human Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 3697
Gene Symbol: ITIH1
ITIH1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.400 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 4054
Gene Symbol: LTBP3
LTBP3
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.400 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 23245
Gene Symbol: ASTN2
ASTN2
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.400 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 3371
Gene Symbol: TNC
TNC
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.400 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.400 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.400 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.400 Biomarker CTD_human Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 27145
Gene Symbol: FILIP1
FILIP1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.400 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 4010
Gene Symbol: LMX1B
LMX1B
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.400 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.300 Biomarker CTD_human Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 56616
Gene Symbol: DIABLO
DIABLO
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.300 Biomarker CTD_human Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.150 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.110 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019